Anti-alpha 1 Antichymotrypsin 抗体, prediluted (ab921)

製品の概要

  • 製品名Anti-alpha 1 Antichymotrypsin antibody, prediluted
    alpha 1 Antichymotrypsin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to alpha 1 Antichymotrypsin, prediluted
  • 特異性The antibody is specific for human alpha-1-antichymotrypsin. This antibody stains monocytes and macrophages in human tissues and does not stain any other cell type.
  • アプリケーション適用あり: IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Human
    非交差種: Mouse, Rat, Sheep, Horse, Cow, Cat, Dog, Pig
  • 免疫原

    Alpha-1-antichymotrypsin isolated from human serum.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab921 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
IHC-Fr
  • 追加情報This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections.
    No further titration is required.
    We suggest an incubation period of 30-60 minutes at room temperature.
    However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.
  • ターゲット情報

    • 機能Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
    • 組織特異性Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.
    • 関連疾患Defects in SERPINA3 may be a cause of chronic obstructive pulmonary disease (COPD) [MIM:107280].
    • 配列類似性Belongs to the serpin family.
    • ドメインThe reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the carboxyl group of the serpin reactive site and the serine hydroxyl of the protease. The resulting inactive serpin-protease complex is highly stable.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • SERPINA3 antibody
      • AACT antibody
      • AACT_HUMAN antibody
      • ACT antibody
      • Alpha-1-antichymotrypsin His-Pro-less antibody
      • Antichymotrypsin antibody
      • Cell growth inhibiting gene 24/25 protein antibody
      • Cell growth-inhibiting gene 24/25 protein antibody
      • GIG24 antibody
      • GIG25 antibody
      • Growth inhibiting protein 24 antibody
      • Growth inhibiting protein 25 antibody
      • MGC88254 antibody
      • Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase, antitrypsin) member 3 antibody
      • Serine (or cysteine) proteinase inhibitor clade A member 3 antibody
      • Serine proteinase inhibitor clade A member 3 antibody
      • Serpin A3 antibody
      • Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3 antibody
      • SERPINA3 antibody
      see all

    Anti-alpha 1 Antichymotrypsin antibody, prediluted 画像

    • Immunohistochemical analysis of formalin-fixed paraffin-embedded human tonsil tissue sections, labelling ?-1-Antichymotrypsin with ab921.

    Anti-alpha 1 Antichymotrypsin antibody, prediluted (ab921) 使用論文

    ab921 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"