製品の概要

  • 製品名Anti-ALOXE3 antibody
    ALOXE3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ALOXE3
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Recombinant Human ALOXE3.

  • ポジティブ・コントロール
    • Human fetal lung lysate, Human fetal skin tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab118470 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 81 kDa.
IHC-P 1/100 - 1/500.

ターゲット情報

  • 機能Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known.
  • 組織特異性Predominantly expressed in skin.
  • パスウェイLipid metabolism; leukotriene D4 biosynthesis.
  • 関連疾患Defects in ALOXE3 are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE) [MIM:242100]. NCIE is a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affected individuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membrane subsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than in lamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. In contrast to lamellar ichthyoses, scales are usually white, fine and powdery, and palms and soles are severely affected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and loss of pulp volume.
  • 配列類似性Belongs to the lipoxygenase family.
    Contains 1 lipoxygenase domain.
    Contains 1 PLAT domain.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ALOXE3 antibody
    • Arachidonate lipoxygenase 3 antibody
    • e LOX 3 antibody
    • E LOX antibody
    • e-LOX-3 antibody
    • eLOX3 antibody
    • Epidermal lipoxygenase antibody
    • Epidermis-type lipoxygenase 3 antibody
    • Lipoxygenase 3 antibody
    • LOXE3_HUMAN antibody
    see all

Anti-ALOXE3 antibody 画像

  • Anti-ALOXE3 antibody (ab118470) at 1/500 dilution + Human fetal lung lysate

    Predicted band size : 81 kDa
  • Staining of Human ALOXE3 in a Formalin/PFA-fixed paraffin-embedded section of Human fetal skin using ab118470 at a dilution of 1/100.

Anti-ALOXE3 antibody (ab118470) 使用論文

ab118470 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"