製品の概要

  • 製品名Anti-ALG9 antibody
    ALG9 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ALG9
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide between amino acids 532-559 from the C terminal region of Human ALG9 (NP_001071159.1, NP_001071160.1, NP_001071158.1, NP_079016.2).

  • ポジティブ・コントロール
    • Ramos cell line lysates

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG

アプリケーション

Our Abpromise guarantee covers the use of ab107072 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 70 kDa.

ターゲット情報

  • 機能Catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides.
  • 組織特異性Ubiquitously expressed; with highest levels in heart, liver and pancreas.
  • パスウェイProtein modification; protein glycosylation.
  • 関連疾患Note=A chromosomal aberration involving ALG9 is found in a family with bipolar affective disorder. Translocation t(9;11)(p24;q23). However, common variations in ALG9 do not play a major role in predisposition to bipolar affective disorder.
    Defects in ALG9 are the cause of congenital disorder of glycosylation type 1L (CDG1L) [MIM:608776]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • 配列類似性Belongs to the glycosyltransferase 22 family.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ALG9 antibody
    • ALG9_HUMAN antibody
    • Alpha-1,2-mannosyltransferase ALG9 antibody
    • Asparagine-linked glycosylation protein 9 homolog antibody
    • Disrupted in bipolar disorder protein 1 antibody
    see all

Anti-ALG9 antibody 画像

  • Anti-ALG9 antibody (ab107072) at 1/100 dilution + Ramos cell line lysates at 35 µg

    Predicted band size : 70 kDa

Anti-ALG9 antibody (ab107072) 使用論文

ab107072 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"