製品の概要

  • 製品名Anti-ALG8 antibody
    ALG8 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ALG8
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat
    交差が予測される動物種: Mouse, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 301-350 (LELKLLDPSQ IPRASMTSGL VQQSQHTVLP SVSPSATLIC TLIAILPSVF) of Rat ALG8 (NP_001029299).

  • ポジティブ・コントロール
    • Rat Heart lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110700 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 59 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
  • パスウェイProtein modification; protein glycosylation.
  • 関連疾患Defects in ALG8 are the cause of congenital disorder of glycosylation type 1H (CDG1H) [MIM:608104]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • 配列類似性Belongs to the ALG6/ALG8 glucosyltransferase family.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 3-glucosyltransferase antibody
    • AI447372 antibody
    • ALG 8 antibody
    • ALG8 alpha-1,3-glucosyltransferase antibody
    • alg8 antibody
    • ALG8_HUMAN antibody
    • Asparagine linked glycosylation 8 alpha 1,3 glucosyltransferase homolog antibody
    • Asparagine linked glycosylation 8 homolog yeast, alpha 1,3 glucosyltransferase antibody
    • Asparagine linked glycosylation 8 homolog S. cerevisiae, alpha 1,3 glucosyltransferase antibody
    • Asparagine-linked glycosylation protein 8 homolog antibody
    • CDG1H antibody
    • Dolichyl P Glc Glc1Man9GlcNAc2 PP dolichyl glucosyltransferase antibody
    • Dolichyl P glucose Glc1Man9GlcNAc2 PP dolichyl alpha 1,3 glucosyltransferase antibody
    • Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha 1,3 glucosyltransferase antibody
    • Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase antibody
    • Gm1089 antibody
    • HUSSY 02 antibody
    • MGC2840 antibody
    • MGC74399 antibody
    • Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha 1,3 glucosyltransferase antibody
    • Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1 antibody
    see all

Anti-ALG8 antibody 画像

  • Anti-ALG8 antibody (ab110700) at 1 µg/ml + Rat Heart lysate at 10 µg

    Predicted band size : 59 kDa

Anti-ALG8 antibody (ab110700) 使用論文

ab110700 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"