製品の概要

  • 製品名Anti-ALG11 antibody
    ALG11 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ALG11
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide designed within residues: LSEDLGVQEY VEFKINIPFD ELKNYLSEAT IGLHTMWNEH FGIGVVECMA, corresponding to internal amino acids 360-409 of Human ALG11 (NP_001004127)

  • ポジティブ・コントロール
    • HepG2 cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab84123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol-linked oligosaccharide chain.
  • 関連疾患Defects in ALG11 are the cause of congenital disorder of glycosylation type 1P (CDG1P) [MIM:613661]. A multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • 配列類似性Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
  • 細胞内局在Endoplasmic reticulum. Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AI849156 antibody
    • alg11 antibody
    • ALG11_HUMAN antibody
    • Asparagine-linked glycosylation 11 antibody
    • Asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) antibody
    • Asparagine-linked glycosylation protein 11 homolog antibody
    • AW492253 antibody
    • B230397C21 antibody
    • GT8 antibody
    • KIAA0266 antibody
    • OTTMUSP00000022781 antibody
    • RGD1564725 antibody
    see all

Anti-ALG11 antibody 画像

  • Anti-ALG11 antibody (ab84123) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 56 kDa
    Observed band size : 56 kDa

Anti-ALG11 antibody (ab84123) 使用論文

ab84123 has not yet been referenced specifically in any publications.

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