製品の概要

  • 製品名Anti-ALG1 antibody
    ALG1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ALG1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Cat, Saccharomyces cerevisiae
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 38-87 (VVLGDVGRSP RMQYHALSLA MHGFSVTLLG FCNSKPHDEL LQNNRIQIVG) of Human ALG1 (NP_061982).

  • ポジティブ・コントロール
    • NTERA2 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab81134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1/62500.

ターゲット情報

  • 機能Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.
  • パスウェイProtein modification; protein glycosylation.
  • 関連疾患Defects in ALG1 are the cause of congenital disorder of glycosylation type 1K (CDG1K) [MIM:608540]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • 配列類似性Belongs to the glycosyltransferase 1 family.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
    see all
  • 別名
    • 4-mannosyltransferase antibody
    • Alg1 antibody
    • ALG1_HUMAN antibody
    • asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase) antibody
    • asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae) antibody
    • Asparagine-linked glycosylation protein 1 homolog antibody
    • Beta 1 4 mannosyltransferase antibody
    • Beta-1 antibody
    • CDG1K antibody
    • Chitobiosyldiphosphodolichol beta-mannosyltransferase antibody
    • GDP Man GlcNAc2 PP dolichol mannosyltransferase antibody
    • GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase antibody
    • GDP-mannose-dolichol diphosphochitobiose mannosyltransferase antibody
    • Hmat-1 antibody
    • HMAT1 antibody
    • HMT 1 antibody
    • HMT1 antibody
    • Mannosyltransferase 1 antibody
    • Mannosyltransferase-1 antibody
    • MT 1 antibody
    • MT-1 antibody
    • MT1 antibody
    see all

Anti-ALG1 antibody 画像

  • Anti-ALG1 antibody (ab81134) at 1 µg/ml (in 5% skim milk / PBS buffer) + NTERA2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 52 kDa
    Observed band size : 52 kDa

Anti-ALG1 antibody (ab81134) 使用論文

ab81134 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab81134.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"