機能Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction.
組織特異性High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain. Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole.
パスウェイAmine and polyamine biosynthesis; carnitine biosynthesis.
配列類似性Belongs to the aldehyde dehydrogenase family.
発生段階Strongly expressed in human embryonic brain (gestational age 12 weeks).