製品の概要

  • 製品名Anti-ALDH5A1 antibody
    ALDH5A1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to ALDH5A1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human ALDH5A1 protein (NP_001071.1).

  • ポジティブ・コントロール
    • Human liver tissue lysate, K562 cell lysate and ALDH5A1 transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89627 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa.

ターゲット情報

  • 機能Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
  • 組織特異性Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta.
  • パスウェイAmino-acid degradation; 4-aminobutanoate degradation.
  • 関連疾患Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) [MIM:271980]. SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric acid in physiologic fluids of patients. The disease is characterized by severe ataxia and by mildly retarded psychomotor development.
  • 配列類似性Belongs to the aldehyde dehydrogenase family.
  • 細胞内局在Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Aldedehyde dehydrogenase 5 family antibody
    • Aldehyde dehydrogenase 5 family member A1 antibody
    • Aldehyde dehydrogenase 5A1 antibody
    • Aldehyde dehydrogenase family 5 member A1 antibody
    • ALDH5A 1 antibody
    • Aldh5a1 antibody
    • mitochondrial antibody
    • Mitochondrial succinate semialdehyde dehydrogenase antibody
    • NAD(+) dependent succinic semialdehyde dehydrogenase antibody
    • NAD(+)-dependent succinic semialdehyde dehydrogenase antibody
    • SSADH antibody
    • SSDH antibody
    • SSDH_HUMAN antibody
    • Succinate semialdehyde dehydrogenase antibody
    • Succinate-semialdehyde dehydrogenase antibody
    see all

Anti-ALDH5A1 antibody 画像

  • Anti-ALDH5A1 antibody (ab89627) at 1 µg/ml + human Liver tissue lysate at 50 µg

    Predicted band size : 57 kDa
    Observed band size : ~57 kDa (why is the actual band size different from the predicted?)
  • Anti-ALDH5A1 antibody (ab89627) at 1 µg/ml + K-562 cell lysate at 50 µg

    Predicted band size : 57 kDa
    Observed band size : 57 kDa
    Additional bands at : 35 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-ALDH5A1 antibody (ab89627) at 1 µg/ml

    Lane 1 : ALDH5A1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 57 kDa
    Observed band size : 57 kDa

Anti-ALDH5A1 antibody (ab89627) 使用論文

ab89627 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"