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機能
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
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組織特異性
Plasma.
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関連疾患
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
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配列類似性
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains.
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翻訳後修飾
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid.
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細胞内局在
Secreted.
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Information by UniProt
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製品の状態
There are 2 isoforms produced by alternative splicing.
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別名
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
- Albumin (AA 34) antibody
- cell growth inhibiting protein 42 antibody
- DKFZp779N1935 antibody
- GIG20 antibody
- GIG42 antibody
- growth-inhibiting protein 20 antibody
- OTTHUMP00000220436 antibody
- OTTHUMP00000220438 antibody
- OTTHUMP00000220439 antibody
- PRO0883 antibody
- PRO0903 antibody
- PRO1341 antibody
- PRO1708 antibody
- PRO2044 antibody
- PRO2619 antibody
- PRO2675 antibody
- Serum albumin antibody
- UNQ696/PRO1341 antibody
see all