製品の概要

  • 製品名Anti-ALAD antibody
    ALAD 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to ALAD
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human ALAD, amino acids 1-339 (NP_000022.2)

  • ポジティブ・コントロール
    • Human liver tissue lysate, ALAD transfected 293T cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab88875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 37 kDa.

ターゲット情報

  • 機能Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
  • パスウェイPorphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.
  • 関連疾患Defects in ALAD are the cause of acute hepatic porphyria (AHP) [MIM:612740]. AHP is a form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors.
  • 配列類似性Belongs to the ALADH family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ALAD antibody
    • ALADH antibody
    • ALADR antibody
    • Aminolevulinate dehydratase antibody
    • Aminolevulinate, delta, dehydratase antibody
    • Delta aminolevulinic acid dehydratase antibody
    • Delta-aminolevulinic acid dehydratase antibody
    • HEM2_HUMAN antibody
    • Lv antibody
    • MGC5057 antibody
    • OTTMUSP00000009376 antibody
    • OTTMUSP00000009377 antibody
    • PBGS antibody
    • Porphobilinogen synthase antibody
    • RP11-10I9.1 antibody
    • RP24-189G18.9 antibody
    see all

Anti-ALAD antibody 画像

  • Anti-ALAD antibody (ab88875) at 1 µg/ml + human liver tissue lysate at 50 µg

    Predicted band size : 37 kDa
    Observed band size : 37 kDa
    Additional bands at : 20 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-ALAD antibody (ab88875) at 1 µg/ml

    Lane 1 : ALAD transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 37 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)

Anti-ALAD antibody (ab88875) 使用論文

ab88875 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"