製品の概要

  • 製品名Anti-ALAD antibody
    ALAD 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ALAD
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae, Drosophila melanogaster, Zebrafish
  • 免疫原

    A region within synthetic peptide: SVMSYSAKFA SCFYGPFRDA AKSSPAFGDR RCYQLPPGAR GLALRAVDRD, corresponding to amino acids 192-241 of Human ALAD

  • ポジティブ・コントロール
    • Jurkat cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab59013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.25 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
  • パスウェイPorphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.
  • 関連疾患Defects in ALAD are the cause of acute hepatic porphyria (AHP) [MIM:612740]. AHP is a form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors.
  • 配列類似性Belongs to the ALADH family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ALAD antibody
    • ALADH antibody
    • ALADR antibody
    • Aminolevulinate dehydratase antibody
    • Aminolevulinate, delta, dehydratase antibody
    • Delta aminolevulinic acid dehydratase antibody
    • Delta-aminolevulinic acid dehydratase antibody
    • HEM2_HUMAN antibody
    • Lv antibody
    • MGC5057 antibody
    • OTTMUSP00000009376 antibody
    • OTTMUSP00000009377 antibody
    • PBGS antibody
    • Porphobilinogen synthase antibody
    • RP11-10I9.1 antibody
    • RP24-189G18.9 antibody
    see all

Anti-ALAD antibody 画像

  • All lanes : Anti-ALAD antibody (ab59013) at 0.25 µg/ml

    Lane 1 : Molecular weight markers
    Lane 2 : Jurkat cell lysate at 10 µg

    Secondary
    Lane 2 : HRP conjugated anti-Rabbit IgG at 1/50000 dilution


    Predicted band size : 37 kDa
    Observed band size : 37 kDa

Anti-ALAD antibody (ab59013) 使用論文

ab59013 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab59013.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"