製品の概要

  • 製品名Anti-AKR7A2 antibody
    AKR7A2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to AKR7A2
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the N-terminal region of human AKR7A2.

  • ポジティブ・コントロール
    • Mouse liver golgi apparatus lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab82397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50 - 1/100. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
ELISA 1/1000.

ターゲット情報

  • 機能Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
  • 組織特異性Detected in brain, liver, small intestine and testis, and at lower levels in heart, prostate, skeletal muscle and spleen. Detected in kidney proximal and distal tubules, endothelial cells lining the Bowman's capsules and some cysts. Detected at low levels in lung and pancreas (at protein level). Widely expressed.
  • 配列類似性Belongs to the aldo/keto reductase 2 family.
  • 細胞内局在Golgi apparatus. Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AFAR antibody
    • AFAR1 antibody
    • AFB1 aldehyde reductase 1 antibody
    • AFB1 AR1 antibody
    • AFB1-AR 1 antibody
    • AFB1AR1 antibody
    • Aflatoxin aldehyde reductase antibody
    • Aflatoxin B1 aldehyde reductase member 2 antibody
    • Aflatoxin beta1 aldehyde reductase antibody
    • Aiar antibody
    • AKR7 antibody
    • Akr7a2 antibody
    • Aldo keto reductase family 7 antibody
    • Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase antibody
    • Aldo keto reductase family 7 member A2 antibody
    • Aldo keto reductase family 7, member A2 (aflatoxin aldehyde reductase) antibody
    • Aldoketoreductase 7 antibody
    • ARK72_HUMAN antibody
    • SSA reductase antibody
    • Succinic semialdehyde reductase antibody
    see all

Anti-AKR7A2 antibody 画像

  • Anti-AKR7A2 antibody (ab82397) at 1/50 dilution + Mouse liver tissue lysates at 12.5 µg

    Predicted band size : 40 kDa
    Observed band size : 40 kDa
    Additional bands at : 35 kDa. We are unsure as to the identity of these extra bands.

Anti-AKR7A2 antibody (ab82397) 使用論文

ab82397 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"