The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. Predicted molecular weight: 36 kDa.
Use a concentration of 5 µg/ml.
Use a concentration of 10 µg/ml.
機能Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
組織特異性Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
配列類似性Belongs to the aldo/keto reductase family.
細胞内局在Lysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.
ab109998, at 10 µg/ml, staining AKR1B10 in HeLa cells by immunoflourescence.
Anti-AKR1B10 antibody [1A6] (ab109998) 使用論文
This product has been referenced in:
Agyeman AS et al. Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles. Breast Cancer Res Treat132:175-87 (2012).
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