製品の概要

  • 製品名Anti-AKR1A1 antibody - C-terminal
    AKR1A1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to AKR1A1 - C-terminal
  • アプリケーション適用あり: IHC-P, ELISA, WBmore details
  • 種交差性
    交差種: Human
  • ポジティブ・コントロール
    • Y79 cell line lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab71228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/10 - 1/50.
ELISA 1/1000.
WB 1/50 - 1/100. Predicted molecular weight: 37 kDa.

ターゲット情報

  • 機能Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
  • 組織特異性Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.
  • 配列類似性Belongs to the aldo/keto reductase family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AK1A1_HUMAN antibody
    • Akr1a1 antibody
    • Alcohol dehydrogenase [NADP+] antibody
    • Alcohol dehydrogenase antibody
    • Aldehyde reductase antibody
    • Aldo keto reductase family 1 member A1 (aldehyde reductase) antibody
    • Aldo-keto reductase family 1 member A1 antibody
    • ALDR1 antibody
    • ALR antibody
    • ARM antibody
    • DD3 antibody
    • MGC12529 antibody
    • MGC1380 antibody
    see all

Anti-AKR1A1 antibody - C-terminal 画像

  • Anti-AKR1A1 antibody - C-terminal (ab71228) at 1/60 dilution + Y79 cell line lysates at 35 µg

    Predicted band size : 37 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
  • ab71228 at 1/50 dilution staining AKR1A1 - C-terminal in human Hepatocarcinoma tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections). A peroxidase conjugated secondary antibody was used followed by DAB staining.

Anti-AKR1A1 antibody - C-terminal (ab71228) 使用論文

ab71228 has not yet been referenced specifically in any publications.

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