製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to AKAP12
  • 特異性
    ab118365 is expected to recognize isoform 1 (NP_005091.2) only.
  • 種交差性

    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    SPDTNGPKLTEEGD

    with a Cysteine residue linker, corresponding to internal sequence amino acids 1645-1658 of Mouse AKAP12 (NP_112462.1).

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab118365 is purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

  • 追加情報
    Is unsuitable for WB.
  • ターゲット情報

    • 機能
      Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC).
    • 組織特異性
      Expressed in endothelial cells, cultured fibroblasts and osteosarcoma, but not in platelets, leukocytes, monocytic cell lines or peripherical blood cells.
    • 配列類似性
      Contains 3 AKAP domains.
    • ドメイン
      Polybasic regions located between residues 266 and 557 are involved in binding PKC.
    • 翻訳後修飾
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在
      Cytoplasm > cell cortex. Cytoplasm > cytoskeleton. May be part of the cortical cytoskeleton.
    • Information by UniProt
    • 参照データベース
    • 別名
      • A kinase (PRKA) anchor protein (gravin) 12 antibody
      • A kinase Anchor Protein 12 antibody
      • A kinase anchor protein 250kDa antibody
      • A-kinase anchor protein 12 antibody
      • A-kinase anchor protein 250 kDa antibody
      • AKA12_HUMAN antibody
      • AKAP 12 antibody
      • AKAP 250 antibody
      • AKAP-12 antibody
      • Akap12 antibody
      • AKAP250 antibody
      • DKFZp686M0430 antibody
      • DKFZp686O0331 antibody
      • FLJ20945 antibody
      • FLJ97621 antibody
      • Gercelin antibody
      • Gravin antibody
      • Kinase scaffold protein gravin antibody
      • Myasthenia gravis autoantigen antibody
      • Myasthenia gravis autoantigen gravin antibody
      • OTTHUMP00000017426 antibody
      • OTTHUMP00000017427 antibody
      • Src-Suppressed C Kinase Substrate antibody
      • Srcs5 antibody
      • SSeCKS antibody
      • Tsga12 antibody
      see all

    参考文献

    ab118365 has not yet been referenced specifically in any publications.

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