製品の概要

  • 製品名Anti-AIMP3/p18 antibody
    AIMP3/p18 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to AIMP3/p18
  • 特異性ab31543 reacts specifically with 21kDa p18 and immunoprecipitates with ATM/ATR
  • アプリケーション適用あり: WB, IP, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Native full length recombinant human p18

  • ポジティブ・コントロール
    • HEK293 cell, U2OS cell and Hela cell

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.05% Sodium Azide
  • 精製度Whole antiserum
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab31543 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/8000. Detects a band of approximately 21 kDa (predicted molecular weight: 18 kDa).
IP Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

ターゲット情報

  • 機能Positive modulator of ATM response to DNA damage.
  • 組織特異性Down-regulated in various cancer tissues.
  • 配列類似性Contains 1 GST C-terminal domain.
  • 細胞内局在Cytoplasm. Nucleus. Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AIMP 3 antibody
    • AIMP3 antibody
    • Aminoacyl tRNA synthetase complex interacting multifunctional protein 3 antibody
    • Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3 antibody
    • ARS interacting multifunctional protein 3 antibody
    • EEF1E1 antibody
    • Elongation factor p18 antibody
    • Eukaryotic translation elongation factor 1 epsilon 1 antibody
    • Eukaryotic translation elongation factor 1 epsilon-1 antibody
    • Homolog of rat elongation factor p18 antibody
    • MCA3_HUMAN antibody
    • Multisynthase complex auxiliary component p18 antibody
    • Multisynthetase complex auxiliary component p18 antibody
    • p18 antibody
    • p18 component of aminoacyl tRNA synthetase complex antibody
    see all

Anti-AIMP3/p18 antibody 画像

  • Anti-AIMP3/p18 antibody (ab31543) at 1/20000 dilution + HEK293 cell line

    Predicted band size : 18 kDa
    Observed band size : 21 kDa (why is the actual band size different from the predicted?)
  • Anti-AIMP3/p18 antibody (ab31543) at 1/8000 dilution + whole cell lysate prepared from HEK293 cells at 50 µg/ml

    Secondary
    Goat anti-rabbit IgG (H+L) at 1/10000 dilution

    Predicted band size : 18 kDa
    Observed band size : 20 kDa (why is the actual band size different from the predicted?)

Anti-AIMP3/p18 antibody (ab31543) 使用論文

This product has been referenced in:
  • Gulati P  et al. Role for the obesity-related FTO gene in the cellular sensing of amino acids. Proc Natl Acad Sci U S A 110:2557-62 (2013). WB ; Mouse . Read more (PubMed: 23359686) »
  • Du Y  et al. Elevation of Highly Up-regulated in Liver Cancer (HULC) by Hepatitis B Virus X Protein Promotes Hepatoma Cell Proliferation via Down-regulating p18. J Biol Chem 287:26302-11 (2012). WB ; Human . Read more (PubMed: 22685290) »

See all 4 Publications for this product

Product Wall

Thank you for contacting us and reporting the problems observed with your current batch of ab31543. As discussed over the phone, it may be that unfortunately you have received a faulty batch. I have organised for a free of charge replacement to be...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"