Anti-AIM2 抗体 (ab119791)
Key features and details
- Rabbit polyclonal to AIM2
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-AIM2 antibody
AIM2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to AIM2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Rat -
免疫原
Synthetic peptide conjugated to a carrier protein, corresponding to residues in the N terminal of Human AIM2.
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ポジティブ・コントロール
- Jurkat whole cell lysate (ab7899); Mouse macrophages treated with IFN gamma and LPS.
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特記事項
Do not aliquot.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.1% BSA -
Concentration information loading...
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精製度
Protein A purified -
特記事項(精製)
This antibody was affinity purified using AIM2 (N-terminal region) peptide (without carrier). -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab119791の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).
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特記事項 |
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WB
1/1000. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa). |
ターゲット情報
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機能
Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity. -
組織特異性
Expressed in spleen, small intestine, peripheral blood leukocytes, and testis. -
配列類似性
Belongs to the HIN-200 family.
Contains 1 DAPIN domain.
Contains 1 HIN-200 domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 9447 Human
- Entrez Gene: 383619 Mouse
- Entrez Gene: 304987 Rat
- Omim: 604578 Human
- SwissProt: O14862 Human
- SwissProt: Q91VJ1 Mouse
- Unigene: 281898 Human
- Unigene: 131453 Mouse
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別名
- Absent in melanoma 2 antibody
- AIM 2 antibody
- Aim2 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab119791 は 4 報の論文で使用されています。
- Jarabicová I et al. Analysis of necroptosis and its association with pyroptosis in organ damage in experimental pulmonary arterial hypertension. J Cell Mol Med 26:2633-2645 (2022). PubMed: 35393789
- Chen J et al. Atorvastatin ameliorates early brain injury after subarachnoid hemorrhage via inhibition of pyroptosis and neuroinflammation. J Cell Physiol 236:6920-6931 (2021). PubMed: 33792028
- Lee S et al. AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence. Nature 597:415-419 (2021). PubMed: 34471287
- Li Y et al. Sevoflurane attenuates cardiomyocyte apoptosis by mediating the miR-219a/AIM2/TLR4/MyD88 axis in myocardial ischemia/reperfusion injury in mice. Cell Cycle 19:1665-1676 (2020). PubMed: 32449438