Anti-AIFM3 抗体 (ab106359)
Key features and details
- Rabbit polyclonal to AIFM3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-AIFM3 antibody
AIFM3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to AIFM3 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human AIFM3 (N terminal). 16 amino acid peptide
Database link: Q96NN9 -
ポジティブ・コントロール
- Human tissue lysates and Human brain tissue
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 2.68% PBS -
Concentration information loading...
-
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106359の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa.
|
|
IHC-P |
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.
|
特記事項 |
---|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa. |
IHC-P
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol. |
ターゲット情報
-
機能
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. -
組織特異性
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level). -
配列類似性
Belongs to the FAD-dependent oxidoreductase family.
Contains 1 Rieske domain. -
ドメイン
The Rieske domain induces apoptosis. -
細胞内局在
Mitochondrion. Does not translocate to the nucleus upon induction of apoptosis. - Information by UniProt
-
参照データベース
- Entrez Gene: 150209 Human
- SwissProt: Q96NN9 Human
- Unigene: 723246 Human
-
別名
- AIFL antibody
- Aifm3 antibody
- AIFM3_HUMAN antibody
see all
画像
-
Lane 1 : Anti-AIFM3 antibody (ab106359) at 1 µg/ml
Lane 2 : Anti-AIFM3 antibody (ab106359) at 2 µg/ml
All lanes : Human brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 67 kDa -
Immunohistochemical staining of human brain tissue using ab106359 at 2.5 µg
-
Immunohistochemistry of AIFM3 in Human brain tissue with ab106359 at 20 ug/mL.
プロトコール
データシートおよび資料
-
Datasheet download
参考文献 (1)
ab106359 は 1 報の論文で使用されています。
- Araujo AN et al. Comprehensive Assessment of Copy Number Alterations Uncovers Recurrent AIFM3 and DLK1 Copy Gain in Medullary Thyroid Carcinoma. Cancers (Basel) 13:N/A (2021). PubMed: 33435319