製品の概要

  • 製品名Anti-AHRR antibody
    AHRR 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to AHRR
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide from the N terminal region of Human AHRR.

  • ポジティブ・コントロール
    • Human fetal testis tissue. Human fetal lung, testis and spleen lysates.

製品の特性

  • 製品の状態Lyophilised:Reconstitute with 200ul distilled H2O. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.2
    Preservative: 0.02% Sodium azide
    Constituents: 1% BSA, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab108518 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/2000. Predicted molecular weight: 76 kDa.
IHC-P 1/100 - 1/500.

ターゲット情報

  • 機能Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
  • 組織特異性Highly expressed in testis, lung, ovary, spleen and pancreas. Highly expressed in mononuclear cells (MNCs) from umbilical cord blood. Isoform 3 is highly expressed in lung, kidney, spleen and thymus. Down-regulated malignant tissue from different anatomical origins, including colon, breast, lung, stomach, cervix, and ovary.
  • 配列類似性Contains 1 basic helix-loop-helix (bHLH) domain.
    Contains 1 PAS (PER-ARNT-SIM) domain.
  • 細胞内局在Cytoplasm. Nucleus. Predominantly in the nuclear compartment. First cytoplasmic, translocates into the nuclear compartment upon interaction with ARNT in the cytoplasmic compartment.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AHH antibody
    • AhR repressor antibody
    • AhRR antibody
    • AHRR_HUMAN antibody
    • aryl hydrocarbon hydroxylase regulator antibody
    • aryl hydrocarbon receptor regulator antibody
    • Aryl hydrocarbon receptor repressor antibody
    • Arylhydrocarbon receptor repressor antibody
    • bHLHe77 antibody
    • Class E basic helix-loop-helix protein 77 antibody
    • Dioxin receptor repressor antibody
    • KIAA1234 antibody
    • MGC167813 antibody
    • MGC176630 antibody
    • OTTHUMP00000221488 antibody
    • OTTHUMP00000221489 antibody
    see all

Anti-AHRR antibody 画像

  • All lanes : Anti-AHRR antibody (ab108518) at 1/1000 dilution

    Lane 1 : Fetal testis lysate
    Lane 2 : Fetal lung lysate
    Lane 3 : Fetal spleen lysate


    Predicted band size : 76 kDa
  • ab108518 at 1/100 dilution showing cytoplasmic and nuclear staining of AHRR in formalin-fixed, paraffin-embedded Human fetal testis by Immunohistochemistry.

Anti-AHRR antibody (ab108518) 使用論文

ab108518 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your interest in ab108518. All of the information we currently have regarding this antibody is available on our online datasheet. At this time, no one has reported the use of this product to us in T-cells. However, we guarantee this ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"