製品の概要

  • 製品名
    AH 6809
  • 製品の詳細
    EP1 and EP2 antagonist
  • 生理活性の詳細
    EP1 and EP2 antagonist (Ki values are 333 and 350 nM, respectively). Specific DP2 receptor antagonist (pA2 = 4.45).
  • 精製度
    > 98%

製品の特性

参考文献

This product has been referenced in:
  • Jones RL & Woodward DF Interaction of prostanoid EP3 and TP receptors in guinea-pig isolated aorta: contractile self-synergism of 11-deoxy-16,16-dimethyl PGE2. Br J Pharmacol 162:521-31 (2011). Read more (PubMed: 20955363) »
  • van der Merwe JQ  et al. Prostaglandin E2 derived from cyclooxygenases 1 and 2 mediates intestinal epithelial ion transport stimulated by the activation of protease-activated receptor 2. J Pharmacol Exp Ther 329:747-52 (2009). Read more (PubMed: 19190238) »
  • Kiriyama M  et al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 122:217-24 (1997). Read more (PubMed: 9313928) »
  • Keery RJ & Lumley P AH6809, a prostaglandin DP-receptor blocking drug on human platelets. Br J Pharmacol 94:745-54 (1988). Read more (PubMed: 2460179) »

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