製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      CRKLGTAMNPCSRT
    • 領域
      120 to 132

関連製品

特性

Our Abpromise guarantee covers the use of ab45721 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-AGRP antibody (ab32882)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

関連情報

  • 別名
    • Agouti related neuropeptide
    • Agouti Related Protein Homolog
    • Agouti-related protein
    • Agrp
    • AGRP_HUMAN
    • AGRT
    • ART
    • ASIP2
    see all
  • 機能
    Plays a role in weight homeostasis. Plays a role in the central control of feeding. Reduces food intake. Inhibits cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Acts primarily on MC3R and MC4R. Has very low activity with MC5R.
  • 組織特異性
    Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.
  • 関連疾患
    Genetic variations in AGRP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
  • 配列類似性
    Contains 1 agouti domain.
  • ドメイン
    The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.
  • 細胞内局在
    Secreted. Golgi apparatus lumen.
  • Information by UniProt

AGRP peptide (120-132) (ab45721) 使用論文

ab45721 has not yet been referenced specifically in any publications.

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The molecular weight of the AGRP peptide (120-132) (ab45721) is 1537.87 g/mol. This therefore equates to 1537870 mg/mol.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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