The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 175 kDa.
機能Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
組織特異性Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle.
関連疾患Glycogen storage disease 3
配列類似性Belongs to the glycogen debranching enzyme family.
翻訳後修飾The N-terminus is blocked. Ubiquitinated.
細胞内局在Cytoplasm. Under glycogenolytic conditions localizes to the nucleus.