製品の概要

  • 製品名Anti-Aggrecan antibody
    Aggrecan 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Aggrecan
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide against C-terminal domain of Human Aggrecan (NP_037359.2) conjugated to KLH.

  • ポジティブ・コントロール
    • Human Cartilage

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab118610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 関連性Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS.
  • 細胞内局在Secreted; extracellular matrix.
  • 参照データベース
  • 別名
    • ACAN antibody
    • AGC 1 antibody
    • AGC1 antibody
    • AGCAN antibody
    • Aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) antibody
    • Aggrecan 1 antibody
    • Aggrecan core protein antibody
    • Aggrecan proteoglycan antibody
    • Aggrecan structural proteoglycan of cartilage antibody
    • Aggrecan1 antibody
    • ATEGQV antibody
    • Cartilage specific proteoglycan core protein antibody
    • Chondroitin sulfate proteoglycan 1 antibody
    • Chondroitin sulfate proteoglycan 1 large aggregating proteoglycan antigen identified by monoclonal antibody A0122 antibody
    • Chondroitin sulfate proteoglycan core protein 1 antibody
    • CSPG 1 antibody
    • CSPG1 antibody
    • CSPGCP antibody
    • JSCATE antibody
    • Large aggregating proteoglycan antibody
    • mcspg antibody
    • mgsk16 antibody
    • MSK 16 antibody
    • MSK16 antibody
    • SEDK antibody
    see all

Anti-Aggrecan antibody 画像

  • ab118610 at 3 µg/ml staining Aggrecan in Formalin-fixed, Paraffin-embedded Human Cartilage tissue by Immunohistochemistry.

Anti-Aggrecan antibody (ab118610) 使用論文

ab118610 has not yet been referenced specifically in any publications.

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Leider habe ich eine schlechte Nachricht für Sie: Aggrecan hat insgesamt eine Übereinstimmung von 19%, es gibt eine Region zwischen AS 800-850 des menschlichen Proteins, welches eine hoh...

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I am sorry to confirm that as far as we are aware, ab118610has never been tested with samples from sheep. All tested and guaranteedspecies cross-reactivity information is sta...

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Thank you for contacting us. We need more information on the use of ab11570 and ab8610 in alphaLISA. Could you please answer the following questions? - Are you going to use these antibodies together or in combination with other antibodies? - ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"