製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to AF10
  • アプリケーション
    適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide (Human) from the C-terminal region of AF10, conjugated to KLH.

  • ポジティブ・コントロール
    • Jurkat cell lysate Human testis tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab71448 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 109 kDa (predicted molecular weight: 109 kDa).
IHC-P 1/10 - 1/50.

ターゲット情報

  • 機能
    Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.
  • 組織特異性
    Expressed abundantly in testis.
  • 関連疾患
    A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with KMT2A/MLL1. The result is a rogue activator protein.
    A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.
  • 配列類似性
    Contains 1 C2HC pre-PHD-type zinc finger.
    Contains 2 PHD-type zinc fingers.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AF 10 antibody
    • AF10 antibody
    • AF10_HUMAN antibody
    • ALL 1 fused gene from chromosome 10 antibody
    • ALL1 fused gene from chromosome 10 antibody
    • ALL1-fused gene from chromosome 10 protein antibody
    • DKFZp686E10210 antibody
    • MGC75086 antibody
    • MLLT 10 antibody
    • MLLT10 antibody
    • Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog Drosophila) translocated to 10 antibody
    • Myeloid/lymphoid or mixed lineage leukemia translocated to 10 antibody
    • OTTHUMP00000045273 antibody
    • Protein AF 10 antibody
    • Protein AF-10 antibody
    • Protein AF10 antibody
    • Type I AF10 protein antibody
    see all

画像

  • Anti-AF10 antibody (ab71448) at 1/100 dilution + Jurkat cell lysate at 12.5 µg

    Predicted band size : 109 kDa
    Observed band size : 109 kDa
    Additional bands at : 25 kDa,45 kDa,55 kDa. We are unsure as to the identity of these extra bands.
  • Formalin-fixed and paraffin-embedded human testis tissue labelled with ab71448 at 1/10 dilution. DAB staining.

参考文献

ab71448 has not yet been referenced specifically in any publications.

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