Anti-Adiponectin Receptor 2 抗体 - Aminoterminal end (ab53399)

製品の概要

  • 製品名Anti-Adiponectin Receptor 2 antibody - Aminoterminal end
    Adiponectin Receptor 2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Adiponectin Receptor 2 - Aminoterminal end
  • アプリケーション適用あり: WB, ICC, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide:

    CSRTPEPDIRLRKGHQLDGTRRGDNDSHQG

    , corresponding to N terminal amino acids 11-40 of Human Adiponectin Receptor 2

  • ポジティブ・コントロール
    • Human liver; human muscle;

アプリケーション

Our Abpromise guarantee covers the use of ab53399 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 44 kDa.
ICC 1/400.
IHC-P Use at an assay dependent dilution.

ターゲット情報

  • 機能Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.
  • 組織特異性Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
  • 配列類似性Belongs to the ADIPOR family.
  • ドメインThe N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • 細胞内局在Membrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • 参照データベース
  • 別名
    • PAQR2 antibody
    • ACDCR2 antibody
    • Adiponectin receptor protein 2 antibody
    • Adipor2 antibody
    • ADR2_HUMAN antibody
    • Progestin and adipoQ receptor family member II antibody
    see all

Anti-Adiponectin Receptor 2 antibody - Aminoterminal end 画像

  • IH paraffin section human liver with ab53399 at a dilution of 1/250.
  • IH paraffin section human muscle with ab53399 at a dilution of 1/250.

Anti-Adiponectin Receptor 2 antibody - Aminoterminal end (ab53399) 使用論文

This product has been referenced in:
  • Fang F  et al. Adiponectin attenuates angiotensin II-induced oxidative stress in renal tubular cells through AMPK and cAMP-Epac signal transduction pathways. Am J Physiol Renal Physiol 304:F1366-74 (2013). Read more (PubMed: 23535586) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"