Anti-Adiponectin Receptor 2 抗体 (ab77613)

製品の概要

  • 製品名Anti-Adiponectin Receptor 2 antibody
    Adiponectin Receptor 2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Adiponectin Receptor 2
  • 特異性Recognizes ADPR2 Receptor. Likely to cross react with ADPR1 Receptor.
  • アプリケーション適用あり: WB, IHC-P, ICCmore details
  • 種交差性
    交差種: Mouse, Rat, Human, Macaque Monkey
    交差が予測される動物種: Chicken, Cow, Pig
  • 免疫原

    Synthetic peptide:

    YITGAALYAARIPERFFPGKC

    , corresponding to C terminal amino acids 321-341 of human Adiponectin Receptor 2

  • ポジティブ・コントロール
    • Human liver tissue and human muscle tissue
  • 特記事項


    This antibody may be used in developing sandwitch ELISA assays in combination with antibodies specific to N terminus of ADPR2 Receptor.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab77613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 44 kDa.
IHC-P 1/250.

Buffer used: 10 mM KHPO4, 140 mM NaCl, pH 7.2.

ICC 1/400.

Acetone fixed cells.

ターゲット情報

  • 機能Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.
  • 組織特異性Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
  • 配列類似性Belongs to the ADIPOR family.
  • ドメインThe N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • 細胞内局在Membrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • 参照データベース
  • 別名
    • PAQR2 antibody
    • ACDCR2 antibody
    • Adiponectin receptor protein 2 antibody
    • Adipor2 antibody
    • ADR2_HUMAN antibody
    • Progestin and adipoQ receptor family member II antibody
    see all

Anti-Adiponectin Receptor 2 antibody 画像

  • Paraffin section of human liver tissue stained with antibody to human ADPR2 receptor C-terminus ab77613 at 1/250 dilution.
  • Paraffin section of human muscle tissue stained with antibody to human ADPR2 receptor C-terminus ab77613 at 1/250 dilution.

Anti-Adiponectin Receptor 2 antibody (ab77613) 使用論文

ab77613 has not yet been referenced specifically in any publications.

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