Anti-Adiponectin Receptor 2 抗体 (ab113538)

製品の概要

  • 製品名
    Anti-Adiponectin Receptor 2 antibody
    Adiponectin Receptor 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Adiponectin Receptor 2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Macaque monkey, Gorilla
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Adiponectin Receptor 2.

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Human Liver tissue lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113538 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).

ターゲット情報

  • 機能
    Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.
  • 組織特異性
    Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
  • 配列類似性
    Belongs to the ADIPOR family.
  • ドメイン
    The N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • 細胞内局在
    Membrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • 参照データベース
  • 別名
    • PAQR2 antibody
    • ACDCR2 antibody
    • Adiponectin receptor protein 2 antibody
    • Adipor2 antibody
    • ADR2_HUMAN antibody
    • Progestin and adipoQ receptor family member II antibody
    see all

画像

  • Anti-Adiponectin Receptor 2 antibody (ab113538) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 43 kDa
    Observed band size : 43 kDa
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 1 minute

プロトコール

参考文献

ab113538 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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