Adiponectin Receptor 1 peptide (361-375) (ab45719)

製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      RYGLEGGCTDDTLL
    • 領域
      361 to 375

特性

Our Abpromise guarantee covers the use of ab45719 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • ACDCR1
    • ADIPO R1
    • Adiponectin receptor protein 1
    • ADIPOR 1
    • Adipor1
    • ADR1_HUMAN
    • CGI 45
    • CGI 45 protein
    • CGI-45
    • CGI45
    • CGI45 protein
    • FLJ25385
    • FLJ42464
    • PAQR1
    • Progestin and adipoQ receptor family member I
    • TESBP1A
    see all
  • 機能
    Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.
  • 組織特異性
    Widely expressed. Highly expressed in skeletal muscle. Expressed at intermediate level in brain, heart, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine.
  • 配列類似性
    Belongs to the ADIPOR family.
  • ドメイン
    The N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • 細胞内局在
    Membrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt

参考文献

ab45719 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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