Anti-Adiponectin Receptor 1 抗体 [mAbcam50675] (ab50675)

製品の概要

  • 製品名Anti-Adiponectin Receptor 1 antibody [mAbcam50675]
    Adiponectin Receptor 1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [mAbcam50675] to Adiponectin Receptor 1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Chicken, Zebrafish
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 350 to the C-terminus of Human Adiponectin Receptor 1.

    (Peptide available as ab59184.)

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Human Skeletal Muscle Lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Concentrated Culture Supernatant
  • 特記事項(精製)Tissue culture supernatant was concentrated and then buffer exchanged.
  • ポリ/モノモノクローナル
  • クローン名mAbcam50675
  • ミエローマSp2/0-Ag14
  • アイソタイプIgM
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab50675 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 10 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).

ターゲット情報

  • 機能Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.
  • 組織特異性Widely expressed. Highly expressed in skeletal muscle. Expressed at intermediate level in brain, heart, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine.
  • 配列類似性Belongs to the ADIPOR family.
  • ドメインThe N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • 細胞内局在Membrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ACDCR1 antibody
    • ADIPO R1 antibody
    • Adiponectin receptor protein 1 antibody
    • ADIPOR 1 antibody
    • Adipor1 antibody
    • ADR1_HUMAN antibody
    • CGI 45 antibody
    • CGI 45 protein antibody
    • CGI-45 antibody
    • CGI45 antibody
    • CGI45 protein antibody
    • FLJ25385 antibody
    • FLJ42464 antibody
    • PAQR1 antibody
    • Progestin and adipoQ receptor family member I antibody
    • TESBP1A antibody
    see all

Anti-Adiponectin Receptor 1 antibody [mAbcam50675] 画像

  • Anti-Adiponectin Receptor 1 antibody [mAbcam50675] (ab50675) at 10 µg/ml + Human skeletal muscle tissue lysate - total protein (ab29330) at 20 µg

    Secondary
    Goat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 42 kDa
    Observed band size : 42 kDa
    Additional bands at : 28 kDa. We are unsure as to the identity of these extra bands.

Anti-Adiponectin Receptor 1 antibody [mAbcam50675] (ab50675) 使用論文

ab50675 has not yet been referenced specifically in any publications.

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