Anti-Adenylosuccinate Lyase 抗体 (ab67516)

製品の概要

  • 製品名Anti-Adenylosuccinate Lyase antibody
    Adenylosuccinate Lyase 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to Adenylosuccinate Lyase
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein (Human)

  • ポジティブ・コントロール
    • Adenylosuccinate Lyase transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab67516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 55 kDa (predicted molecular weight: 55 kDa).

ターゲット情報

  • 組織特異性Ubiquitously expressed. Both isoforms are produced by all tissues. Isoform 2 is 10-fold less abundant than isoform 1.
  • パスウェイPurine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.
    Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.
  • 関連疾患Defects in ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency) [MIM:103050]. ADSL deficiency is an autosomal recessive disorder characterized by the accumulation in the body fluids of succinylaminoimidazole-carboxamide riboside (SAICA-riboside) and succinyladenosine (S-Ado). Most children display marked psychomotor delay, often accompanied by epilepsy or autistic features, or both, although some patients may be less profoundly retarded. Occasionally, growth retardation and muscular wasting are also present.
  • 配列類似性Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Adenylosuccinase antibody
    • Adenylosuccinate lyase antibody
    • ADSL antibody
    • AMPS antibody
    • ASase antibody
    • ASL antibody
    • OTTHUMP00000199172 antibody
    • OTTHUMP00000199173 antibody
    • PUR8_HUMAN antibody
    see all

Anti-Adenylosuccinate Lyase antibody 画像

  • All lanes : Anti-Adenylosuccinate Lyase antibody (ab67516) at 1/500 dilution

    Lane 1 : Adenylosuccinate Lyase transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

    Predicted band size : 55 kDa
    Observed band size : 55 kDa

Anti-Adenylosuccinate Lyase antibody (ab67516) 使用論文

ab67516 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"