製品の概要

  • 製品名Anti-Adducin antibody
    Adducin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Adducin
  • 特異性ab58480 detects endogenous levels of total ADD1 protein.
  • アプリケーション適用あり: IHC-P, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic non-phosphopeptide derived from human ADD1 around the phosphorylation site of threonine 445 (E-K-TP-R-W).

  • ポジティブ・コントロール
    • Huamn breast carcinoma tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab58480 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
ELISA 1/10000.

ターゲット情報

  • 関連性Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
  • 細胞内局在Cytoplasm › cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 参照データベース
  • 別名
    • ADD1 antibody
    • ADD2 antibody
    • ADD3 antibody
    • ADDA antibody
    • ADDB antibody
    • ADDL antibody
    • Adducin 1 (alpha) antibody
    • Adducin 1 antibody
    • Adducin 2 (beta) antibody
    • Adducin 2 antibody
    • Adducin 3 (gamma) antibody
    • Adducin 3 antibody
    • Adducin like antibody
    • Alpha adducin antibody
    • Beta adducin antibody
    see all

Anti-Adducin antibody 画像

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab58480 at a dilution of 1/50. Right hand image: treated with immunising peptide. Left hand image: untreated.

Anti-Adducin antibody (ab58480) 使用論文

ab58480 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"