製品の概要

  • 製品名Anti-ACVRL1 antibody
    ACVRL1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ACVRL1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to Human ACVRL1 (C terminal).
    Database link: NM_020661

  • ポジティブ・コントロール
    • Human hepatocellular carcinoma tissue and Human fetal heart lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab93595 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報IHC-P: 1/100 - 1/300.
    WB: 1/200 - 1/5000. Predicted molecular weight: 56 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May bind activin as well.
    • 関連疾患Defects in ACVRL1 are the cause of hereditary hemorrhagic telangiectasia type 2 (HHT2) [MIM:600376]; also known as Osler-Rendu-Weber syndrome 2 (ORW2). HHT2 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary, cerebral and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia.
    • 配列類似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
      Contains 1 GS domain.
      Contains 1 protein kinase domain.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Activin A receptor antibody
      • Activin A receptor type II like 1 antibody
      • Activin A receptor, type II like kinase 1 antibody
      • Activin receptor like kinase 1 antibody
      • Activin receptor-like kinase 1 antibody
      • ACVL1_HUMAN antibody
      • ACVRL1 antibody
      • ACVRLK1 antibody
      • ALK-1 antibody
      • ALK1 antibody
      • HHT antibody
      • HHT2 antibody
      • ORW2 antibody
      • Osler Rendu Weber syndrome 2 antibody
      • Serine/threonine protein kinase receptor R3 antibody
      • Serine/threonine-protein kinase receptor R3 antibody
      • SKR3 antibody
      • TGF B superfamily receptor type I antibody
      • TGF-B superfamily receptor type I antibody
      • TSR-I antibody
      • TSR1 antibody
      see all

    Anti-ACVRL1 antibody 画像

    • Anti-ACVRL1 antibody (ab93595) at 1/200 dilution + Human fetal heart lysate

      Predicted band size : 56 kDa
    • Immunohistochemical staining of formalin-fixed paraffin-embedded hepatocellular liver carcinoma using ab93595 at 1/100 dilution.

    Anti-ACVRL1 antibody (ab93595) 使用論文

    ab93595 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab93595.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"