Anti-Activin A Receptor Type IC 抗体 (ab65088)

製品の概要

  • 製品名Anti-Activin A Receptor Type IC antibody
    Activin A Receptor Type IC 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Activin A Receptor Type IC
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human Activin A Receptor Type IC.

    (Peptide available as ab74349.)

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Human spleen tissue lysate. It also gave positive results in Human lung, ovary, placenta, heart, testis and kidney (data not shown).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab65088 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 2 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 55 kDa).

ターゲット情報

  • 機能Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
  • 組織特異性Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
  • 配列類似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Activin A receptor, type IC antibody
    • Activin receptor like kinase 7 antibody
    • Activin receptor type 1C precursor antibody
    • Activin receptor type IC antibody
    • Activin receptor type-1C antibody
    • Activin receptor-like kinase 7 antibody
    • ACTR IC antibody
    • ACTR-IC antibody
    • ACTRIC antibody
    • ACV1C_HUMAN antibody
    • Acvr1c antibody
    • ACVRLK7 antibody
    • ALK 7 antibody
    • ALK-7 antibody
    • ALK7 antibody
    see all

Anti-Activin A Receptor Type IC antibody 画像

  • Anti-Activin A Receptor Type IC antibody (ab65088) at 2 µg/ml + Human spleen tissue lysate - total protein (ab29699) at 20 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 55 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)


    Exposure time : 30 seconds

Anti-Activin A Receptor Type IC antibody (ab65088) 使用論文

ab65088 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab65088.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"