Anti-Activin A Receptor Type IC 抗体 (ab111121)

製品の概要

  • 製品名Anti-Activin A Receptor Type IC antibody
    Activin A Receptor Type IC 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Activin A Receptor Type IC
  • 特異性ab111121 detects endogenous levels of total Activin A Receptor Type IC protein.
  • アプリケーション適用あり: IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from an internal sequence of Human Activin A Receptor Type IC.

  • ポジティブ・コントロール
    • COS7 cells, Human brain tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/500.

ターゲット情報

  • 機能Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
  • 組織特異性Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
  • 配列類似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Activin A receptor, type IC antibody
    • Activin receptor like kinase 7 antibody
    • Activin receptor type 1C precursor antibody
    • Activin receptor type IC antibody
    • Activin receptor type-1C antibody
    • Activin receptor-like kinase 7 antibody
    • ACTR IC antibody
    • ACTR-IC antibody
    • ACTRIC antibody
    • ACV1C_HUMAN antibody
    • Acvr1c antibody
    • ACVRLK7 antibody
    • ALK 7 antibody
    • ALK-7 antibody
    • ALK7 antibody
    see all

Anti-Activin A Receptor Type IC antibody 画像

  • Immunofluorescence analysis of Activin A Receptor Type IC in COS7 cells, using ab111121 at a 1/100 dilution. The imge on the right is from cells treated with the synthesized peptide.
  • ab111121, at a 1/50 dilution, staining Activin A Receptor Type IC in paraffin embedded Human brain tissue by Immunohistochemistry. The image on the right is from cells treated with the synthesized peptide.

Anti-Activin A Receptor Type IC antibody (ab111121) 使用論文

ab111121 has not yet been referenced specifically in any publications.

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