Anti-Activin A Receptor Type IB 抗体 [MM0054-11A7] (ab78415)

製品の概要

  • 製品名Anti-Activin A Receptor Type IB antibody [MM0054-11A7]
    Activin A Receptor Type IB 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MM0054-11A7] to Activin A Receptor Type IB
  • 特異性ab78415 detects Activin A Receptor Type IB (ALK4). No cross reactivity was found to Activin A Receptor Type IA (ALK2).
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant human Activin A Receptor Type IB extracellular domain

  • 特記事項


    This antibody was produced from a hybridoma (mouse myeloma) fused with spleen cells from an immunized mouse.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab78415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/1000. Predicted molecular weight: 57 kDa.
IHC-P 1/50.

ターゲット情報

  • 機能On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Phosphorylates TDP2.
  • 組織特異性Expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver.
  • 配列類似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Autophosphorylated.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 製品の状態There are 3 isoforms produced by alternative splicing. Isoform 1 also known as SKR2-1; isoform 2 as SKR2-2; isoform 3 as SKR2-3.
  • 別名
    • Activin A receptor type 1B antibody
    • Activin A receptor type II like kinase 4 antibody
    • Activin A type 1B receptor antibody
    • Activin A type IB receptor antibody
    • Activin receptor like kinase 4 antibody
    • Activin receptor type 1B antibody
    • Activin receptor type IB antibody
    • Activin receptor type-1B antibody
    • Activin receptor-like kinase 4 antibody
    • ACTR IB antibody
    • ACTR-IB antibody
    • ACTRIB antibody
    • ACV1B_HUMAN antibody
    • ACVR 1B antibody
    • Acvr1b antibody
    • ACVRLK 4 antibody
    • ACVRLK4 antibody
    • ALK 4 antibody
    • ALK-4 antibody
    • ALK4 antibody
    • Serine(threonine) protein kinase receptor R2 antibody
    • Serine/threonine-protein kinase receptor R2 antibody
    • SKR 2 antibody
    • SKR2 antibody
    see all

Anti-Activin A Receptor Type IB antibody [MM0054-11A7] 画像

  • ab78415 at 1/50 dilution, staining Activin A Receptor Type IB in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections).

Anti-Activin A Receptor Type IB antibody [MM0054-11A7] (ab78415) 使用論文

ab78415 has not yet been referenced specifically in any publications.

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