製品の概要

  • 製品名Anti-Activin A Receptor Type IB antibody
    Activin A Receptor Type IB 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Activin A Receptor Type IB
  • 特異性At least three isoforms of ACVR1B are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1C.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Human Activin A Receptor Type IB (C terminal). ACVR1B antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human ACVR1B.
    Database link: P36896

  • ポジティブ・コントロール
    • Human kidney tissue lysate
  • 特記事項

    Antibodies should not be exposed to prolonged high temperatures.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab77049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa.

ターゲット情報

  • 機能On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Phosphorylates TDP2.
  • 組織特異性Expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver.
  • 配列類似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Autophosphorylated.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 製品の状態There are 3 isoforms produced by alternative splicing. Isoform 1 also known as SKR2-1; isoform 2 as SKR2-2; isoform 3 as SKR2-3.
  • 別名
    • Activin A receptor type 1B antibody
    • Activin A receptor type II like kinase 4 antibody
    • Activin A type 1B receptor antibody
    • Activin A type IB receptor antibody
    • Activin receptor like kinase 4 antibody
    • Activin receptor type 1B antibody
    • Activin receptor type IB antibody
    • Activin receptor type-1B antibody
    • Activin receptor-like kinase 4 antibody
    • ACTR IB antibody
    • ACTR-IB antibody
    • ACTRIB antibody
    • ACV1B_HUMAN antibody
    • ACVR 1B antibody
    • Acvr1b antibody
    • ACVRLK 4 antibody
    • ACVRLK4 antibody
    • ALK 4 antibody
    • ALK-4 antibody
    • ALK4 antibody
    • Serine(threonine) protein kinase receptor R2 antibody
    • Serine/threonine-protein kinase receptor R2 antibody
    • SKR 2 antibody
    • SKR2 antibody
    see all

Anti-Activin A Receptor Type IB antibody 画像

  • All lanes : Anti-Activin A Receptor Type IB antibody (ab77049) at 1 µg/ml

    Lane 1 : human kidney tissue lysate
    Lane 2 : human kidney tissue lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 57 kDa
    Observed band size : 66 kDa (why is the actual band size different from the predicted?)

Anti-Activin A Receptor Type IB antibody (ab77049) 使用論文

This product has been referenced in:
  • Colas AR  et al. Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis. Genes Dev 26:2567-79 (2012). Read more (PubMed: 23152446) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"