Anti-Activin A Receptor Type IB 抗体 (ab64813)


  • 製品名Anti-Activin A Receptor Type IB antibody
    Activin A Receptor Type IB 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Activin A Receptor Type IB
  • アプリケーション適用あり: WB, ELISA, ICC/IF, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide derived from an internal region of human Activin A Receptor Type IB

  • ポジティブ・コントロール
    • Hela cells or 293 cell lines. Heart.



Our Abpromise guarantee covers the use of ab64813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa).
ELISA 1/5000.
ICC/IF 1/500 - 1/1000.
IHC-P Use at an assay dependent concentration.


  • 機能On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Phosphorylates TDP2.
  • 組織特異性Expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver.
  • 配列類似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Autophosphorylated.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 製品の状態There are 3 isoforms produced by alternative splicing. Isoform 1 also known as SKR2-1; isoform 2 as SKR2-2; isoform 3 as SKR2-3.
  • 別名
    • Activin A receptor type 1B antibody
    • Activin A receptor type II like kinase 4 antibody
    • Activin A type 1B receptor antibody
    • Activin A type IB receptor antibody
    • Activin receptor like kinase 4 antibody
    • Activin receptor type 1B antibody
    • Activin receptor type IB antibody
    • Activin receptor type-1B antibody
    • Activin receptor-like kinase 4 antibody
    • ACTR IB antibody
    • ACTR-IB antibody
    • ACTRIB antibody
    • ACV1B_HUMAN antibody
    • ACVR 1B antibody
    • Acvr1b antibody
    • ACVRLK 4 antibody
    • ACVRLK4 antibody
    • ALK 4 antibody
    • ALK-4 antibody
    • ALK4 antibody
    • Serine(threonine) protein kinase receptor R2 antibody
    • Serine/threonine-protein kinase receptor R2 antibody
    • SKR 2 antibody
    • SKR2 antibody
    see all

Anti-Activin A Receptor Type IB antibody 画像

  • Immunofluorescence analysis of HeLa cells using ab64813 at a 1:500 dilution.
    Left image untreated.
    Right image treated with peptide.
  • All lanes : Anti-Activin A Receptor Type IB antibody (ab64813) at 1/500 dilution

    Lane 1 : Extracts from 293 cells
    Lane 2 : Extracts from mouse heart
    Lane 3 : Extracts from mouse heart cells immunizing peptide at 5 µg

    Lysates/proteins at 10 µg per lane.

    Predicted band size : 57 kDa
    Observed band size : 57 kDa
  • ab64813 staining Activin A Receptor Type IB in human lymph node tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded tissue sections). The sections were fixed in paraformaldehyde prior to blocking with 10% serum for 1 hour at 20°C. The primary antibody was diluted 1/250 and incubated with the sample for 12 hours at 4°C. An HRP-conjugated goat anti-rabbit polyclonal was used as the secondary antibody, diluted 1/200.

    See Abreview

Anti-Activin A Receptor Type IB antibody (ab64813) 使用論文

This product has been referenced in:
  • Peng Y  et al. Critical roles of miRNA-mediated regulation of TGFß signalling during mouse cardiogenesis. Cardiovasc Res 103:258-67 (2014). Mouse . Read more (PubMed: 24835278) »

See 1 Publication for this product

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Ich habe gute Neuigkeiten: ich werde das Datenblatt des ab109300 heute oder morgen noch mit dem neuen ICC Bild auf den neusten Stand bringen. Desweiteren habe ich dies an ebenfalls als weitere Email an sie ge...

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Ich habe mich in die Materie gearbeitet und herausgefunden, dass dieses sich Protein zwischen der Zellmembran und dem Zytoplasma hin und her bewegt.

Unser Labor hat zwar im Moment kein Bild vom ab10...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (Lymph node)
Specification Lymph node
Fixative Paraformaldehyde
Antigen retrieval step None
Permeabilization No
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 20°C

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投稿 Jun 02 2011