製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human

関連製品

特性

Our Abpromise guarantee covers the use of ab39861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    This peptide is used for blocking the activity of the Anti-RHEB antibody (ab25873).
  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • Ras homolog enriched in brain 2, formerly
    • GTP binding protein Rheb
    • GTP-binding protein Rheb
    • MGC111559
    • Ras homolog enriched in brain
    • Ras homolog enriched in brain 2
    • Rheb
    • RHEB 2
    • RHEB_HUMAN
    • RHEB2
    • RHEB2, formerly
    see all
  • 機能
    Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.
  • 組織特異性
    Ubiquitous. Highest levels observed in skeletal and cardiac muscle.
  • 配列類似性
    Belongs to the small GTPase superfamily. Rheb family.
  • 翻訳後修飾
    Farnesylation is important for efficiently activating mTORC1-mediated signaling.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt

参考文献

ab39861 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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