Active human Parathyroid Hormone peptide (ab68899)

製品の概要

製品の詳細

  • 由来
    Synthetic
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      LMH NLGKHLNSME RVEWLRKKLQ DVHNF
    • 分子量
      3 kDa
    • 領域
      7 to 34

特性

Our Abpromise guarantee covers the use of ab68899 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    The activity calculated by UMR106 cell/cAMP method corresponds to a specific activity of 1.0 x 104 Units/mg.
  • アプリケーション

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.
    Purity is greater than 97.0% as determined by analysis by RP-HPLC and SDS-PAGE, purified by proprietary chromatographic techniques.
  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 4% Mannitol, 20mM PBS, pH 7

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    Reconstitute in sterile 18MOhm/cm water to not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

関連情報

  • 別名
    • hPTH
    • Parathormone
    • Parathyrin
    • Parathyroid hormone
    • Parathyroid hormone 1
    • Prepro PTH
    • Preproparathyroid hormone
    • PTH
    • PTH1
    • PTH1 receptor
    • PTH1R
    • PTHR
    • PTHR1
    • PTHY_HUMAN
    see all
  • 機能
    PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
  • 関連疾患
    Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
  • 配列類似性
    Belongs to the parathyroid hormone family.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab68899 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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