Anti-Actin 抗体 (Biotin) (ab113279)

製品の概要

  • 製品名Anti-Actin antibody (Biotin)
    Actin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Actin (Biotin)
  • 標識Biotin
  • 特異性The epitope recognized by ab113279 maps to the N-terminus of Human Beta-actin using the numbering given in Swiss-Prot entry P60709 (GeneID 60). The N-terminus of Beta-Actin is highly conserved with Gamma-Actin and preliminary indications are that ab113279 also recognizes Gamma- Actin
  • アプリケーション適用あり: WBmore details
    適用なし: IP
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Sheep, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Chimpanzee, Snake, a wide range of other species, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis , Medaka fish
  • 免疫原

    Synthetic peptide corresponding to Human Actin (N terminal).

  • ポジティブ・コントロール
    • HeLa whole cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/5000 - 1/15000. Predicted molecular weight: 42 kDa.
  • 追加情報Is unsuitable for IP.
  • ターゲット情報

    • 機能Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
    • 関連疾患Defects in ACTA1 are the cause of nemaline myopathy type 3 (NEM3) [MIM:161800]. A form of nemaline myopathy. Nemaline myopathies are muscular disorders characterized by muscle weakness of varying severity and onset, and abnormal thread-or rod-like structures in muscle fibers on histologic examination. The phenotype at histological level is variable. Some patients present areas devoid of oxidative activity containg (cores) within myofibers. Core lesions are unstructured and poorly circumscribed.
      Defects in ACTA1 are a cause of myopathy congenital with excess of thin myofilaments (MPCETM) [MIM:161800]. A congenital muscular disorder characterized at histological level by areas of sarcoplasm devoid of normal myofibrils and mitochondria, and replaced with dense masses of thin filaments. Central cores, rods, ragged red fibers, and necrosis are absent.
      Defects in ACTA1 are a cause of congenital myopathy with fiber-type disproportion (CFTD) [MIM:255310]; also known as congenital fiber-type disproportion myopathy (CFTDM). CFTD is a genetically heterogeneous disorder in which there is relative hypotrophy of type 1 muscle fibers compared to type 2 fibers on skeletal muscle biopsy. However, these findings are not specific and can be found in many different myopathic and neuropathic conditions.
    • 配列類似性Belongs to the actin family.
    • 細胞内局在Cytoplasm > cytoskeleton.
    • Information by UniProt
    • 参照データベース
    • 別名
      • a actin antibody
      • ACTA antibody
      • ACTA1 antibody
      • Actin alpha skeletal muscle antibody
      • Actin antibody
      • actin, alpha 1, skeletal muscle 1 antibody
      • actin, alpha 1, skeletal muscle antibody
      • Actin, alpha skeletal muscle antibody
      • actina antibody
      • actine antibody
      • ACTS_HUMAN antibody
      • aktin antibody
      • Alpha Actin 1 antibody
      • Alpha skeletal muscle Actin antibody
      • alpha skeletal muscle antibody
      • alpha-actin antibody
      • Alpha-actin-1 antibody
      • ASMA antibody
      • CFTD antibody
      • CFTD1 antibody
      • CFTDM antibody
      • MPFD antibody
      • NEM1 antibody
      • NEM2 antibody
      • NEM3 antibody
      • nemaline myopathy type 3 antibody
      see all

    Anti-Actin antibody (Biotin) 画像

    • All lanes : Anti-Actin antibody (Biotin) (ab113279) at 0.07 µg/ml

      Lane 1 : HeLa whole cell lysate at 50 µg
      Lane 2 : HeLa whole cell lysate at 15 µg
      Lane 3 : HeLa whole cell lysate at 5 µg

      Developed using the ECL technique

      Predicted band size : 42 kDa


      Exposure time : 30 seconds

    Anti-Actin antibody (Biotin) (ab113279) 使用論文

    ab113279 has not yet been referenced specifically in any publications.

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    Thank you for your patience.

    I just received an update form lab regarding the epitope for ab79667 and ab113279. Unfortunately the epitope has not been determined so the information is not available. I am sorry we will not be able to suggest th...

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    Thank you for contacting us.

    I can confirm that I am still waiting for information from lab. I will send you the epitoope details of ab79667 as soon as I receive them.

    The other possible combination of ab8227 in sandwich ELISA would b...

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    Merci pour votre appel de hier. Je suis désolée du retard de ma réponse.

    Voici le lien pour nos kits de conjugaision: http://www.abcam.com/easylink

    et voici aussi le code pour le test promis:
    xx

    J...

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