製品の概要

  • 製品名Anti-Acrolein antibody
    Acrolein 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Acrolein
  • 特異性This antibody targets conjugated acrolein. This antibody does not recognize free acrolein
  • アプリケーション適用あり: IHC-Fr, IHC-Pmore details
  • 免疫原

    Chemical/ Small Molecule corresponding to Acrolein conjugated to Bovine Serum Albumin (BSA).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab37110 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr 1/500 - 1/1000. (cryostat)
IHC-P Use at an assay dependent concentration. PubMed: 21953681

ターゲット情報

  • 関連性Acrolein, a reactive alpha,beta-unsaturated aldehyde, is a common environmental pollutant, a metabolite of the anticancer drug cyclophosphamide, and a byproduct of lipid peroxidation. An increase in acrolein production has been proposed as a marker for Alzheimer's disease, diabetic glomerular lesions, and atherosclerosis. Acrolein is a potent inhibitor of cell proliferation at nonlethal doses and may act through effects on redox-regulated transcription factors. It has been reported that NF-kappaB activation is inhibited by acrolein.
  • 別名
    • 2-Propen-1-one antibody
    • 2-propenal antibody
    • Acraldehyde antibody
    • Acrolein antibody
    • Acrylic aldehyde antibody
    see all

Anti-Acrolein antibody (ab37110) 使用論文

This product has been referenced in:
  • Shearn CT  et al. Identification of 5' AMP-activated Kinase as a Target of Reactive Aldehydes during Chronic Ingestion of High Concentrations of Ethanol. J Biol Chem 289:15449-15462 (2014). Read more (PubMed: 24722988) »
  • Spiess PC  et al. Acrolein exposure suppresses antigen-induced pulmonary inflammation. Respir Res 14:107 (2013). IHC-P . Read more (PubMed: 24131734) »

See all 7 Publications for this product

Product Wall

Thank you for your inquiry. This antibody is not conjugated, the chemical which was used as the immunogen was conjugated with BSA. So you can use HRP conjugated second antibody.

Thank you for your reply.

I confirmed with the lab that this assay was done using the same ELISA protocol that we had attached to the earlier email (CCE 3753830). I've attached it again for your reference.

I hope this information helps.

Thank you for your reply,

I've attached the ELISA protocol that is recommended with this antibody.

This product is designed to detect acrolein in the presence of gluteraldehyde.


I hope this information helps. Please...

Read More

Thank you for contacting Abcam regarding ab37110.


This antibody will NOT recognize free acrolein. Only acrolein in the presence of gluteraldehyde. The ELISA performed to QC this antibody and test cross-reactivity was performed with the ...

Read More
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (retina)
Specification retina
Fixative Paraformaldehyde
Permeabilization Yes - 0.1% Triton
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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投稿 Jun 08 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"