製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Aconitase 1
  • 特異性
    ab62701 detects endogenous levels of total Aconitase 1 protein.
  • アプリケーション
    適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic non phosphopeptide derived from human Aconitase 1 around the phosphorylation site of serine 711 (Y-G-SP-R-R).

  • ポジティブ・コントロール
    • Human thyroid gland tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab62701 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
IHC-P
  • 追加情報
    ELISA: 1/20000.
    IHC-P: 1/50 - 1/100.

    ab62701 can detect both of unmodified form and Ser-711 phosphorylated form of Aconitase 1 protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
      Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
    • 配列類似性
      Belongs to the aconitase/IPM isomerase family.
    • 細胞内局在
      Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ACO 1 antibody
      • ACO1 antibody
      • ACOC_HUMAN antibody
      • Aconitase 1 soluble antibody
      • Aconitase antibody
      • Aconitase1 antibody
      • Aconitate hydratase antibody
      • ACONS antibody
      • Citrate hydro lyase antibody
      • Citrate hydro-lyase antibody
      • Cytoplasmic aconitate hydratase antibody
      • Ferritin repressor protein antibody
      • IRE BP 1 antibody
      • IRE-BP 1 antibody
      • IREB 1 antibody
      • IREB1 antibody
      • IREBP antibody
      • IREBP1 antibody
      • Iron regulatory protein 1 antibody
      • Iron responsive element binding protein 1 antibody
      • Iron-responsive element-binding protein 1 antibody
      • IRP 1 antibody
      • IRP1 antibody
      • OTTHUMP00000045233 antibody
      see all

    画像

    • ab62701, at 1/50 dilution, staining Aconitase 1 in paraffin embedded human thyroid gland tissue by Immunohistochemistry in the absence or presence of the immunising peptide.

    プロトコール

    参考文献

    ab62701 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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