製品の概要

  • 製品名Anti-Aconitase 1 antibody
    Aconitase 1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to Aconitase 1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 780-890 of Human Aconitase 1

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab54718 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
      Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
    • 配列類似性Belongs to the aconitase/IPM isomerase family.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ACO 1 antibody
      • ACO1 antibody
      • ACOC_HUMAN antibody
      • Aconitase 1 soluble antibody
      • Aconitase antibody
      • Aconitase1 antibody
      • Aconitate hydratase antibody
      • ACONS antibody
      • Citrate hydro lyase antibody
      • Citrate hydro-lyase antibody
      • Cytoplasmic aconitate hydratase antibody
      • Ferritin repressor protein antibody
      • IRE BP 1 antibody
      • IRE-BP 1 antibody
      • IREB 1 antibody
      • IREB1 antibody
      • IREBP antibody
      • IREBP1 antibody
      • Iron regulatory protein 1 antibody
      • Iron responsive element binding protein 1 antibody
      • Iron-responsive element-binding protein 1 antibody
      • IRP 1 antibody
      • IRP1 antibody
      • OTTHUMP00000045233 antibody
      see all

    Anti-Aconitase 1 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab54718 Aconitase 1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-Aconitase 1 antibody (ab54718) 使用論文

    This product has been referenced in:
    • Haro KJ  et al. Dysregulation of IRP1-mediated iron metabolism causes gamma ray-specific radioresistance in leukemia cells. PLoS One 7:e48841 (2012). WB ; Human . Read more (PubMed: 23155415) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab54718.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"