Rabbit polyclonal to ACMSD
Mouse, Rat, Cow, Zebrafish
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 105 and 307 of Human ACMSD.
Molt-4 and Raji whole cell lysate
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 38 kDa.
Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
Secondary metabolite metabolism; quinolate metabolism.
Belongs to the ACMSD family.
Information by UniProt
2 amino 3 carboxymuconate 6 semialdehyde decarboxylase antibody
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase antibody
has not yet been referenced specifically in any publications.
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