製品の概要

製品の詳細

  • 由来
    Synthetic

特性

Our Abpromise guarantee covers the use of ab8368 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

関連情報

  • 別名
    • ACIN 1
    • ACIN1
    • ACINU_HUMAN
    • Acinus
    • ACN
    • Apoptotic chromatin condensation inducer 1
    • Apoptotic chromatin condensation inducer in the nucleus
    • DKFZp667N107
    • fSAP152
    • functional spliceosome-associated protein 152
    • KIAA0670
    see all
  • 機能
    Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Contains 1 SAP domain.
  • 翻訳後修飾
    Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

参考文献

ab8368 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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