製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Acinus
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to a region between residue 1291 and the C-terminus (residue 1341) of human Acinus (NP_055792.1)

  • ポジティブ・コントロール
    • human basal cell carcinoma and human stomach adenocarcinoma tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500.

ターゲット情報

  • 機能
    Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Contains 1 SAP domain.
  • 翻訳後修飾
    Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ACIN 1 antibody
    • ACIN1 antibody
    • ACINU_HUMAN antibody
    • Acinus antibody
    • ACN antibody
    • Apoptotic chromatin condensation inducer 1 antibody
    • Apoptotic chromatin condensation inducer in the nucleus antibody
    • DKFZp667N107 antibody
    • fSAP152 antibody
    • functional spliceosome-associated protein 152 antibody
    • KIAA0670 antibody
    see all

画像

  • ab84454, at 1/250 dilution, staining Acinus in formalin-fixed, paraffin-embedded stomach adenocarcinoma. by Immunohistochemistry, using DAB detection.
  • ab84454, at 1/250 dilution, staining Acinus in formalin-fixed, paraffin-embedded human basal cell carcinoma. by Immunohistochemistry, using DAB detection.

プロトコール

参考文献

This product has been referenced in:
  • Singh SS  et al. Comparison of ACINUS, caspase-3, and TUNEL as apoptotic markers in determination of tumor growth rates of clinically localized prostate cancer using image analysis. Prostate 69:1603-10 (2009). IHC-P ; Human . Read more (PubMed: 19644955) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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