製品の概要

  • 製品名Anti-Acinus antibody
    Acinus 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Acinus
  • 特異性The antibody recognises three different splice forms of Acinus, designated Acinus L, Acinus S and Acinus S'.
  • アプリケーション適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    DTSENRPENDVPEPP

    , corresponding to amino acids 775-789 of Human Acinus L, 48 to 62 of human Acinus S’, or 17 to 31 of human Acinus S, which differ from those of mouse Acinus by one amino acid.

  • ポジティブ・コントロール
    • K562 whole cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab7354 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF
WB
  • 追加情報ICC/IF: Use at a concentration of 5 µg/ml.
    WB: Use at a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 220 kDa (predicted molecular weight: 151 kDa). Can be blocked with Acinus (internal) peptide (human)


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
    • 組織特異性Ubiquitous.
    • 配列類似性Contains 1 SAP domain.
    • 翻訳後修飾Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ACIN 1 antibody
      • ACIN1 antibody
      • ACINU_HUMAN antibody
      • Acinus antibody
      • ACN antibody
      • Apoptotic chromatin condensation inducer 1 antibody
      • Apoptotic chromatin condensation inducer in the nucleus antibody
      • DKFZp667N107 antibody
      • fSAP152 antibody
      • functional spliceosome-associated protein 152 antibody
      • KIAA0670 antibody
      see all

    Anti-Acinus antibody 画像

    • Immunofluorescence of Acinus in K562 cells with ab7354 at 20 ug/mL.

    • Anti-Acinus antibody (ab7354) at 1 µg/ml + K562 whole cell lysate

      Predicted band size : 151 kDa
    • ab7354 at 5µg/ml staining Acinus in K562 cells by ICC/IF

    Anti-Acinus antibody (ab7354) 使用論文

    ab7354 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab7354.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"