製品の概要

  • 製品名Anti-Acid Phosphatase 2 antibody
    Acid Phosphatase 2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Acid Phosphatase 2
  • アプリケーション適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Dog, Cynomolgus Monkey, Orangutan
  • 免疫原

    Synthetic peptide:

    C-QNETRQTPEYQN

    , corresponding to internal sequence amino acids 166-177 of Human Acid Phosphatase 2

  • ポジティブ・コントロール
    • Human prostate tissue.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab85719 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/16000.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 関連疾患Defects in ACP2 are a cause of acid phosphatase deficiency (ACPHD) [MIM:200950]. The clinical features are intermittent vomiting, hypotonia, lethargy, opisthotonos, terminal bleeding, and death in early infancy. Lysosomal acid phosphatase is deficient in cultured fibroblasts and multiple tissues.
  • 配列類似性Belongs to the histidine acid phosphatase family.
  • 翻訳後修飾The membrane-bound form is converted to the soluble form by sequential proteolytic processing. First, the C-terminal cytoplasmic tail is removed. Cleavage by a lysosomal protease releases the soluble form in the lysosome lumen.
    N-glycosylated. The intermediates formed during enzymatic deglycosylation suggest that all eight predicted N-glycosylation sites are used.
  • 細胞内局在Lysosome membrane. Lysosome lumen. The soluble form arises by proteolytic processing of the membrane-bound form.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Acid phosphatase 2 lysosomal antibody
    • ACP 2 antibody
    • ACP2 antibody
    • LAP antibody
    • Lysosomal acid phosphatase 2 antibody
    • Lysosomal acid phosphatase antibody
    • PPAL_HUMAN antibody
    see all

Anti-Acid Phosphatase 2 antibody 画像

  • ab85719, at 5µg/ml, staining Acid Phosphatase 2 in formalin-fixed, paraffin-embedded Human prostate tissue by Immunohistochemistry.

Anti-Acid Phosphatase 2 antibody (ab85719) 使用論文

ab85719 has not yet been referenced specifically in any publications.

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