製品の概要

  • 製品名Anti-Acid Phosphatase 2 antibody
    Acid Phosphatase 2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to Acid Phosphatase 2
  • アプリケーション適用あり: ICC/IF, IHC-P, WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human, Chimpanzee, Ferret, Chlamydia psittaci, Hepatitis B virus, Orangutan, Scorpion
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-424 of Human Acid Phosphatase 2

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2b
  • 軽鎖の種類lambda
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab54721 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF
IHC-P
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.
    IF/ICC: Use at a concentration of 10 µg/ml.
    IHC-P: Use at a concentration of 5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連疾患Defects in ACP2 are a cause of acid phosphatase deficiency (ACPHD) [MIM:200950]. The clinical features are intermittent vomiting, hypotonia, lethargy, opisthotonos, terminal bleeding, and death in early infancy. Lysosomal acid phosphatase is deficient in cultured fibroblasts and multiple tissues.
    • 配列類似性Belongs to the histidine acid phosphatase family.
    • 翻訳後修飾The membrane-bound form is converted to the soluble form by sequential proteolytic processing. First, the C-terminal cytoplasmic tail is removed. Cleavage by a lysosomal protease releases the soluble form in the lysosome lumen.
      N-glycosylated. The intermediates formed during enzymatic deglycosylation suggest that all eight predicted N-glycosylation sites are used.
    • 細胞内局在Lysosome membrane. Lysosome lumen. The soluble form arises by proteolytic processing of the membrane-bound form.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Acid phosphatase 2 lysosomal antibody
      • ACP 2 antibody
      • ACP2 antibody
      • LAP antibody
      • Lysosomal acid phosphatase 2 antibody
      • Lysosomal acid phosphatase antibody
      • PPAL_HUMAN antibody
      see all

    Anti-Acid Phosphatase 2 antibody 画像

    • Acid Phosphatase 2 antibody (ab54721) used in immunofluorescence at 10ug/ml on HeLa cells.
    • Acid Phosphatase 2 antibody (ab54721) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human lymphoma tissue.
    • Western blot against tagged recombinant protein immunogen using ab54721 Acid Phosphatase 2 antibody at 1ug/ml. Predicted band size of immunogen is 72 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    • ab54721 at 10 ug/ml staining Acid Phosphatase 2 in human Hela cells by Immunocytochemistry / Immunofluorescence.

    Anti-Acid Phosphatase 2 antibody (ab54721) 使用論文

    ab54721 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab54721.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"