Anti-Acetylcholinesterase 抗体 [4E11] (ab17774)

製品の概要

  • 製品名Anti-Acetylcholinesterase antibody [4E11]
    Acetylcholinesterase 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4E11] to Acetylcholinesterase
  • 特異性ab17774 is specific for brain AChE and does not recognize AChE from erythrocytes.
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Cow, Human
    交差が予測される動物種: Rabbit, Cat
  • 免疫原

    Synthetic peptide corresponding to Human Acetylcholinesterase aa 574-583.
    Sequence:

    TDTLDEA ERQ


    Database link: P22303

  • エピトープC-terminal 10 residues (aa 574-583) of human brain acetylcholinesterase.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 特記事項(精製)Protein A/G purified.
  • ポリ/モノモノクローナル
  • クローン名4E11
  • ミエローマx63-Ag8.653
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab17774 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
WB 1/200. Predicted molecular weight: 68 kDa.

ターゲット情報

  • 機能Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
  • 組織特異性Isoform H is highly expressed in erythrocytes.
  • 配列類似性Belongs to the type-B carboxylesterase/lipase family.
  • 細胞内局在Cell membrane; Cell junction > synapse. Secreted. Cell membrane and Nucleus. Only observed in apoptotic nuclei.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ACEE antibody
    • ACES_HUMAN antibody
    • Acetylcholinesterase antibody
    • AChE antibody
    • Apoptosis related acetylcholinesterase antibody
    • ARACHE antibody
    • N ACHE antibody
    • N-ACHE antibody
    • YT antibody
    • YT blood group antibody
    see all

Anti-Acetylcholinesterase antibody [4E11] (ab17774) 使用論文

This product has been referenced in:
  • Boschetti N  et al. Monoclonal antibodies against a C-terminal peptide of human brain acetylcholinesterase distinguish between erythrocyte and brain acetylcholinesterases. Clin Chem 42:19-23 (1996). Read more (PubMed: 8565226) »

See 1 Publication for this product

Product Wall

Merci de nous avoir contactés. Ma collègue m'a expliqué les raisons de votre appel.

1) ab17774: nos produits sont garantis pour fonctionner tels qu'ils sont décrits sur la fiche technique (si le problème nous est communiqué dans les 6 mois qui...

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Thank you for your enquiry. I have taken a closer look at the article the original developers of the antibody published (Boschetti et al. Clinical Chemistry 42:1, 19-23 (1996)). It seems they are using a 5 ug/ml dilution in their Western blotting ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"